Description

optineurin [Source:HGNC Symbol;Acc:HGNC:17142]

Synonyms

TFIIIA-INTP, FIP-2, HYPL, HIP7, NRP, FIP2, GLC1E

Location

Chromosome 10: 13,099,449-13,138,308 forward strand.

GRCh38:CM000672.2

About this gene

This gene has 12 transcripts (splice variants), 65 orthologues, 1 paralogue, is a member of 1 Ensembl protein family and is associated with 4 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
OPTN-005ENST00000378748.73521577aaENSP00000368022
 
Protein coding
CCDS7094Q96CV9 NM_001008211
NM_001008213
NP_001008212
NP_001008214
TSL:1GENCODE basicAPPRIS P2
OPTN-008ENST00000378747.73400577aaENSP00000368021
 
Protein coding
CCDS7094Q96CV9 NM_001008212
NP_001008213
TSL:1GENCODE basicAPPRIS P2
OPTN-007ENST00000378757.63321577aaENSP00000368032
 
Protein coding
CCDS7094Q96CV9 NM_021980
NP_068815
TSL:1GENCODE basicAPPRIS P2
OPTN-006ENST00000263036.92464577aaENSP00000263036
 
Protein coding
CCDS7094Q96CV9 -TSL:2GENCODE basicAPPRIS P2
OPTN-004ENST00000378752.73488571aaENSP00000368027
 
Protein coding
-Q96CV9 -TSL:1GENCODE basicAPPRIS ALT1
OPTN-009ENST00000378764.62498571aaENSP00000368040
 
Protein coding
-Q96CV9 -TSL:5GENCODE basicAPPRIS ALT1
OPTN-001ENST00000424614.1664126aaENSP00000400356
 
Protein coding
-H7C1H4 -CDS 5' incompleteTSL:3
OPTN-012ENST00000486862.1423107aaENSP00000481473
 
Protein coding
-A0A087WY28 -CDS 5' incompleteTSL:3
OPTN-011ENST00000430081.584862aaENSP00000414747
 
Nonsense mediated decay
-X6RKL2 -TSL:5
OPTN-002ENST00000482140.566758aaENSP00000484961
 
Nonsense mediated decay
-A0A087X2G2 -TSL:3
OPTN-003ENST00000469025.1642No protein-
 
Processed transcript
---TSL:3
OPTN-010ENST00000487935.1511No protein-
 
Processed transcript
---TSL:3

Gene-based displays