Description

mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:HGNC:6860]

Synonyms

c-COT, MEKK8, Tpl-2, ESTF, COT, EST

Location

Chromosome 10: 30,433,937-30,461,833 forward strand.

GRCh38:CM000672.2

About this gene

This gene has 7 transcripts (splice variants), 63 orthologues, 8 paralogues, is a member of 1 Ensembl protein family and is associated with 1 phenotype.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP3K8-201ENST00000263056.53096467aaENSP00000263056
 
Protein coding
CCDS7166P41279 NM_005204
NP_005195
TSL:1GENCODE basicAPPRIS P1
MAP3K8-207ENST00000542547.52782467aaENSP00000443610
 
Protein coding
CCDS7166P41279 NM_001244134
NP_001231063
TSL:1GENCODE basicAPPRIS P1
MAP3K8-202ENST00000375321.12518467aaENSP00000364470
 
Protein coding
CCDS7166P41279 NM_001320961
NP_001307890
TSL:1GENCODE basicAPPRIS P1
MAP3K8-205ENST00000415139.51026255aaENSP00000409653
 
Protein coding
-Q5T857 -CDS 3' incompleteTSL:3
MAP3K8-203ENST00000375322.2932132aaENSP00000364471
 
Protein coding
-Q5T854 -TSL:2GENCODE basic
MAP3K8-204ENST00000413724.5776223aaENSP00000391275
 
Protein coding
-Q5T853 -CDS 3' incompleteTSL:3
MAP3K8-206ENST00000430603.1647No protein-
 
Retained intron
---TSL:3

Gene-based displays