Description

DOT1-like histone H3K79 methyltransferase [Source:HGNC Symbol;Acc:HGNC:24948]

Synonyms

DOT1, KIAA1814, KMT4

Location

Chromosome 19: 2,164,149-2,232,578 forward strand.

GRCh38:CM000681.2

About this gene

This gene has 9 transcripts (splice variants), 63 orthologues, is a member of 2 Ensembl protein families and is associated with 193 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
DOT1L-001ENST0000039866574361537aaENSP00000381657
 
Protein coding
CCDS42460Q8TEK3 NM_032482
NP_115871
TSL:1GENCODE basicAPPRIS P1
DOT1L-008ENST000004575902907653aaENSP00000407411
 
Protein coding
-H7C2S2 -CDS 5' incompleteTSL:5
DOT1L-009ENST00000586024725142aaENSP00000476469
 
Protein coding
-V9GY76 -CDS 5' incompleteTSL:3
DOT1L-003ENST00000452696624208aaENSP00000404284
 
Protein coding
-C9JH95 -CDS 3' incompleteTSL:3
DOT1L-007ENST00000446286376125aaENSP00000412916
 
Protein coding
-H7C3N3 -CDS 5' and 3' incompleteTSL:3
DOT1L-004ENST0000047893763869aaENSP00000484015
 
Nonsense mediated decay
-A0A087X1A7 -CDS 5' incompleteTSL:3
DOT1L-006ENST00000608122576No protein-
 
Processed transcript
---TSL:2
DOT1L-010ENST00000591498567No protein-
 
Processed transcript
---TSL:4
DOT1L-002ENST000004824333658No protein-
 
Retained intron
---TSL:2

Gene-based displays