Description

mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127]

Synonyms

FCC2, HNPCC2, COCA2, HNPCC

Location

Chromosome 3: 36,993,332-37,050,918 forward strand.

GRCh38:CM000665.2

About this gene

This gene has 23 transcripts (splice variants), 69 orthologues, is a member of 1 Ensembl protein family and is associated with 42 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MLH1-201ENST00000231790.62752756aaENSP00000231790
 
Protein coding
CCDS2663P40692 NM_000249
NP_000240
TSL:1GENCODE basicAPPRIS P1
MLH1-216ENST00000458205.62608515aaENSP00000402667
 
Protein coding
CCDS54563A0A024R2S9 P40692 NM_001258274
NP_001245203
TSL:1GENCODE basic
MLH1-221ENST00000536378.52567515aaENSP00000444286
 
Protein coding
CCDS54563A0A024R2S9 P40692 NM_001258273
NP_001245202
TSL:2GENCODE basic
MLH1-206ENST00000435176.52428658aaENSP00000402564
 
Protein coding
CCDS54562P40692 NM_001167617
NP_001161089
TSL:2GENCODE basic
MLH1-222ENST00000539477.52366515aaENSP00000443665
 
Protein coding
CCDS54563A0A024R2S9 P40692 NM_001167619
NP_001161091
TSL:2GENCODE basic
MLH1-212ENST00000455445.62296515aaENSP00000398272
 
Protein coding
CCDS54563A0A024R2S9 P40692 NM_001167618
NP_001161090
TSL:2GENCODE basic
MLH1-213ENST00000456676.62230679aaENSP00000416687
 
Protein coding
-H0Y818 NM_001258271
NP_001245200
CDS 5' incompleteTSL:1
MLH1-207ENST00000441265.5917105aaENSP00000398392
 
Protein coding
-E7EUC9 -CDS 3' incompleteTSL:5
MLH1-223ENST00000616768.4721223aaENSP00000480669
 
Protein coding
-A0A087WX20 -CDS 5' incompleteTSL:2
MLH1-204ENST00000429117.556283aaENSP00000407019
 
Protein coding
-C9JZ54 -CDS 3' incompleteTSL:4
MLH1-203ENST00000413740.1342114aaENSP00000416476
 
Protein coding
-H0Y806 -CDS 5' and 3' incompleteTSL:1
MLH1-210ENST00000450420.523361aaENSP00000393006
 
Protein coding
-H0Y4N0 -CDS 5' incompleteTSL:1
MLH1-205ENST00000432299.592848aaENSP00000416783
 
Nonsense mediated decay
-E9PF25 -TSL:1
MLH1-202ENST00000413212.168452aaENSP00000400844
 
Nonsense mediated decay
-H0Y5U4 -CDS 5' incompleteTSL:5
MLH1-214ENST00000457004.566838aaENSP00000407773
 
Nonsense mediated decay
-F2Z298 -TSL:3
MLH1-215ENST00000458009.566095aaENSP00000411066
 
Nonsense mediated decay
-H0Y793 -CDS 5' incompleteTSL:1
MLH1-209ENST00000447829.560858aaENSP00000399329
 
Nonsense mediated decay
-H0Y5L7 -CDS 5' incompleteTSL:1
MLH1-211ENST00000454028.557038aaENSP00000392649
 
Nonsense mediated decay
-F2Z298 -TSL:5
MLH1-208ENST00000442249.555838aaENSP00000387511
 
Nonsense mediated decay
-F2Z298 -TSL:4
MLH1-220ENST00000492474.5589No protein-
 
Processed transcript
---TSL:5
MLH1-219ENST00000485889.1566No protein-
 
Processed transcript
---TSL:5
MLH1-217ENST00000466900.5555No protein-
 
Processed transcript
---TSL:4
MLH1-218ENST00000476172.5429No protein-
 
Processed transcript
---TSL:3

Gene-based displays