Description

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6844]

Synonyms

MKK4, SERK1, PRKMK4, MEK4, JNKK1

Location

Chromosome 17: 12,020,824-12,143,830 forward strand.

GRCh38:CM000679.2

About this gene

This gene has 15 transcripts (splice variants), 76 orthologues, 7 paralogues, is a member of 1 Ensembl protein family and is associated with 27 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K4-202ENST00000415385.73856410aaENSP00000410402
 
Protein coding
CCDS62095P45985 NM_001281435
NP_001268364
TSL:2GENCODE basicAPPRIS ALT2
MAP2K4-201ENST00000353533.93826399aaENSP00000262445
 
Protein coding
CCDS11162P45985 NM_003010
NP_003001
TSL:1GENCODE basicAPPRIS P3
MAP2K4-215ENST00000602811.5113641aaENSP00000473582
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-212ENST00000602375.5106492aaENSP00000473472
 
Nonsense mediated decay
-R4GN37 -TSL:5
MAP2K4-214ENST00000602686.597741aaENSP00000473458
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-211ENST00000602305.596145aaENSP00000473606
 
Nonsense mediated decay
-J3QLE2 -TSL:5
MAP2K4-213ENST00000602537.594841aaENSP00000473511
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-204ENST00000538465.792516aaENSP00000467239
 
Nonsense mediated decay
-K7EP58 -CDS 5' incompleteTSL:5
MAP2K4-207ENST00000582183.555145aaENSP00000463507
 
Nonsense mediated decay
-J3QLE2 -TSL:4
MAP2K4-206ENST00000581941.5813No protein-
 
Processed transcript
---TSL:3
MAP2K4-205ENST00000579089.5571No protein-
 
Processed transcript
---TSL:4
MAP2K4-209ENST00000582897.5482No protein-
 
Processed transcript
---TSL:5
MAP2K4-203ENST00000536413.23852No protein-
 
Retained intron
---TSL:2
MAP2K4-208ENST00000582377.1648No protein-
 
Retained intron
---TSL:3
MAP2K4-210ENST00000585076.1543No protein-
 
Retained intron
---TSL:4

Gene-based displays