Description

defensin, alpha 3, neutrophil-specific [Source:HGNC Symbol;Acc:HGNC:2762]

Synonyms

DEF3, HNP-3

Location
INSDC coordinates

chromosome:GRCh38:CM000670.2:6996837:7018301:1

About this gene

This gene has 2 transcripts (splice variants), 44 orthologues, 5 paralogues, is a member of 1 Ensembl protein family and is associated with 9 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
DEFA3-001ENST0000032785749894aaENSP00000328359
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5962P59666 Q6EZE9 NM_005217
NP_005208
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P2

PRINCIPAL2 - APPRIS candidate principal isoform (CCDS).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

DEFA3-201ENST0000061615038594aaENSP00000484218
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
--NP_001289194
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Gene-based displays