DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986]
Chromosome 20: 41,028,822-41,124,487 forward strand.
GRCh38:CM000682.2
This gene has 6 transcripts (splice variants), 270 orthologues, 1 paralogue and is associated with 61 phenotypes.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
---|---|---|---|---|---|---|---|---|---|
ENST00000361337.3 | TOP1-201 | 3734 | 765aa | ENSP00000354522.2 | Protein coding | CCDS13312 | P11387 | NM_003286.4 | MANE Select, Ensembl Canonical, GENCODE basic, APPRIS P1, TSL:1, |
ENST00000680945.1 | TOP1-202 | 2532 | 296aa | ENSP00000504935.1 | Protein coding | A0A7P0T852 | - | GENCODE basic, | |
ENST00000681113.1 | TOP1-204 | 3938 | 204aa | ENSP00000505788.1 | Nonsense mediated decay | A0A7P0T9R7 | - | - | |
ENST00000681058.1 | TOP1-203 | 8092 | No protein | - | Retained intron | - | - | - | |
ENST00000681392.1 | TOP1-205 | 4782 | No protein | - | Retained intron | - | - | - | |
ENST00000681884.1 | TOP1-206 | 4736 | No protein | - | Retained intron | - | - | - |