Description

checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627]

Synonyms

bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53

Location

Chromosome 22: 28,687,743-28,742,422 reverse strand.

GRCh38:CM000684.2

About this gene

This gene has 24 transcripts (splice variants), 65 orthologues, is a member of 3 Ensembl protein families and is associated with 9 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CHEK2-003ENST000003825801971586aaENSP00000372023
 
Protein coding
CCDS33629O96017 NM_001005735
NP_001005735
TSL:1GENCODE basicAPPRIS ALT2
CHEK2-005ENST000004055981959543aaENSP00000386087
 
Protein coding
CCDS13843O96017 -TSL:5GENCODE basicAPPRIS P3
CHEK2-002ENST000003283541867543aaENSP00000329178
 
Protein coding
CCDS13843O96017 NM_007194
NP_009125
TSL:1GENCODE basicAPPRIS P3
CHEK2-006ENST000004042761785543aaENSP00000385747
 
Protein coding
CCDS13843O96017 -TSL:1GENCODE basicAPPRIS P3
CHEK2-201ENST000003482951771514aaENSP00000329012
 
Protein coding
CCDS13844O96017 NM_145862
NP_665861
TSL:5GENCODE basic
CHEK2-022ENST000004027311545514aaENSP00000384835
 
Protein coding
CCDS13844O96017 -TSL:1GENCODE basic
CHEK2-021ENST000004036421359452aaENSP00000384919
 
Protein coding
-O96017 NM_001257387
NP_001244316
TSL:1GENCODE basic
CHEK2-018ENST00000434810984276aaENSP00000416721
 
Protein coding
-H0Y820 -CDS 5' incompleteTSL:3
CHEK2-013ENST00000439200906295aaENSP00000408065
 
Protein coding
-B7ZBF7 -CDS 3' incompleteTSL:5
CHEK2-010ENST00000447421900298aaENSP00000397478
 
Protein coding
-B7ZBF6 -CDS 3' incompleteTSL:5
CHEK2-011ENST00000425190752121aaENSP00000390244
 
Protein coding
-B7ZBF2 -CDS 3' incompleteTSL:5
CHEK2-012ENST00000398017713172aaENSP00000381099
 
Protein coding
-B7ZBF8 -CDS 3' incompleteTSL:5
CHEK2-202ENST00000382565696207aaENSP00000372006
 
Protein coding
-C9JFD7 -TSL:5GENCODE basic
CHEK2-019ENST00000456369588144aaENSP00000394430
 
Protein coding
-H0Y4V6 -CDS 5' incompleteTSL:3
CHEK2-017ENST00000464581425137aaENSP00000483777
 
Protein coding
-A0A087X102 -CDS 3' incompleteTSL:2
CHEK2-001ENST000004166712560207aaENSP00000402225
 
Nonsense mediated decay
-C9JFD7 -TSL:1
CHEK2-023ENST000004337281580289aaENSP00000404400
 
Nonsense mediated decay
-O96017 -TSL:2
CHEK2-009ENST000004175881551203aaENSP00000412901
 
Nonsense mediated decay
-O96017 -TSL:2
CHEK2-008ENST000004485111532165aaENSP00000404567
 
Nonsense mediated decay
-O96017 -TSL:2
CHEK2-004ENST000004330281349161aaENSP00000403659
 
Nonsense mediated decay
-F8WCV2 -TSL:5
CHEK2-014ENST0000045425272245aaENSP00000387451
 
Nonsense mediated decay
-H7BZ30 -CDS 5' incompleteTSL:3
CHEK2-015ENST0000043934655357aaENSP00000396903
 
Nonsense mediated decay
-H7C0V7 -CDS 5' incompleteTSL:4
CHEK2-016ENST00000491919609No protein-
 
Retained intron
---TSL:3
CHEK2-020ENST00000472807514No protein-
 
Retained intron
---TSL:2

Gene-based displays