Description

prion protein [Source:HGNC Symbol;Acc:HGNC:9449]

Synonyms

AltPrP, CD230, CJD, GSS, PRIP, PRP

Location
INSDC coordinates

chromosome:GRCh38:CM000682.2:4686236:4701590:1

About this gene

This gene has 4 transcripts (splice variants), 44 orthologues, is a member of 1 Ensembl protein family and is associated with 12 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PRNP-002ENST000003794402657253aaENSP00000368752
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13080P04156 Q53YK7 NM_000311
NM_001080121
NM_001080122
NM_001080123
NM_001271561
NM_183079
NP_000302
NP_001073590
NP_001073591
NP_001073592
NP_001258490
NP_898902
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P2

PRINCIPAL2 - APPRIS candidate principal isoform (CCDS).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PRNP-003ENST000004303502539253aaENSP00000399376
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13080P04156 Q53YK7 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P2

PRINCIPAL2 - APPRIS candidate principal isoform (CCDS).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PRNP-001ENST00000457586855217aaENSP00000415284
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-X6RKS3 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PRNP-004ENST00000424424806249aaENSP00000411599
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A2A2V1 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APPRIS ALT1

ALTERNATIVE1 - APPRIS candidate principal isoform that is conserved in at least three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Gene-based displays