Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]

Synonyms

MAPKK1, MEK1, PRKMK1

Location
INSDC coordinates

chromosome:GRCh38:CM000677.2:66386817:66492312:1

About this gene

This gene has 3 transcripts (splice variants), 68 orthologues, 6 paralogues, is a member of 1 Ensembl protein family and is associated with 3 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K1-001ENST000003071023410393aaENSP00000302486
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS10216A4QPA9 Q02750 NM_002755
NP_002746
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
MAP2K1-003ENST000005663261432217aaENSP00000456438
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BRW9 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
MAP2K1-002ENST000004258181338No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays