Description

high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000]

Synonyms

HMG2

INSDC coordinates

chromosome:GRCh38:CM000666.2:173331695:173335125:1

About this gene

This gene has 5 transcripts (splice variants), 68 orthologues, 3 paralogues, is a member of 1 Ensembl protein family and is associated with 33 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
HMGB2-001ENST000002965031889209aaENSP00000296503
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS3816P26583 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
HMGB2-003ENST000004469221175209aaENSP00000393448
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS3816P26583 NM_001130688
NM_002129
NP_001124160
NP_002120
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
HMGB2-004ENST000004387041032209aaENSP00000404912
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS3816P26583 NM_001130689
NP_001124161
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
HMGB2-005ENST00000506267629134aaENSP00000423001
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-D6R9A6 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HMGB2-002ENST000005113161841No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays