Description

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) [Source:HGNC Symbol;Acc:HGNC:6155]

Synonyms

CD18, LFA-1, MAC-1, MFI7

Location
INSDC coordinates

chromosome:GRCh38:CM000683.2:44885953:44931989:1

Transcripts



This gene has 25 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
ITGB2-002ENST000003978503178769 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13716A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 B4E0R1 E5RFI0
E5RHE6 E5RHT0 E5RIG7
E5RK25 E5RK54 E7EVZ9
P05107 Q96PT7
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
ITGB2-201ENST000003023472955769 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13716A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 B4E0R1 E5RFI0
E5RHE6 E5RHT0 E5RIG7
E5RK25 E5RK54 E7EVZ9
P05107 Q96PT7
NM_000211
NP_000202
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
ITGB2-001ENST000003551532913769 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13716A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 B4E0R1 E5RFI0
E5RHE6 E5RHT0 E5RIG7
E5RK25 E5RK54 E7EVZ9
P05107 Q96PT7
NM_001127491
NP_001120963
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
ITGB2-004ENST000003978572813769 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13716A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 B4E0R1 E5RFI0
E5RHE6 E5RHT0 E5RIG7
E5RK25 E5RK54 E7EVZ9
P05107 Q96PT7
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
ITGB2-005ENST000003978522769769 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13716A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 B4E0R1 E5RFI0
E5RHE6 E5RHT0 E5RIG7
E5RK25 E5RK54 E7EVZ9
P05107 Q96PT7
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
ITGB2-003ENST000003978542592712 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A024D9P8 A0A024DAF4 A0A024DAS5
A0A024DAT2 A0A024DBF0 A0A024DBF8
A0A024DBG3 D3DSM0 E5RFI0
E5RHE6 E5RHT0
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITGB2-202ENST000006106222200378 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A024D9P8 A0A024DAS5 A0A024DBF0
A0A024DBF8 E5RFI0 E5RHE6
E5RHT0
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITGB2-010ENST00000320216966322 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A024DAS5 A0A024DBF0 E5RHE6
E5RK54 J3KNI6 Q96PT7
-CDS 5' and 3' incomplete5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-024ENST00000523663680166 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFI0 E5RHE6 E5RHT0
E5RIG7 E5RK25 E5RK54
E7EVZ9 Q96PT7
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-017ENST0000052268860649 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RHE6 E5RK54 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-022ENST00000522931573160 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFI0 E5RHE6 E5RHT0
E5RIG7 E5RK25 E5RK54
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-015ENST00000517563571120 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFI0 E5RHE6 E5RHT0
E5RIG7 E5RK54
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-021ENST0000052425156837 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RHE6 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-014ENST0000052199555649 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RHT0 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-016ENST0000051781952770 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFI0 E5RHT0 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-008ENST00000397846422108 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A8MVG7 E5RHT0 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITGB2-013ENST00000523323282371 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E5RGK9 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-020ENST0000052038956893 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E5RHT0 E5RIE4 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-023ENST00000523126577No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-018ENST00000521987563No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-009ENST00000479849427No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-007ENST000004986664781No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-006ENST000004751702125No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-011ENST00000479202704No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITGB2-019ENST00000518033572No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays