Description

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:8872]

Synonyms

PFRX

Location
INSDC coordinates

chromosome:GRCh38:CM000685.2:54932961:54998534:1

About this gene

This gene has 4 transcripts (splice variants), 72 orthologues, 3 paralogues, is a member of 1 Ensembl protein family and is associated with 92 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PFKFB1-001ENST000003750061929471aaENSP00000364145
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS14364P16118 NM_001271804
NM_002625
NP_001258733
NP_002616
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PFKFB1-202ENST000005456761591406aaENSP00000444074
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS65273P16118 NM_001271805
NP_001258734
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PFKFB1-203ENST000006146861353244aaENSP00000480232
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-I1Z9G3 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PFKFB1-201ENST000003749921156271aaENSP00000364131
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q4VBA9 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).

Gene-based displays