Description

thioredoxin-related transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:15487]

Synonyms

PDIA11, TMX, TXNDC, TXNDC1

Location
INSDC coordinates

chromosome:GRCh38:CM000676.2:51240162:51257546:1

About this gene

This gene has 3 transcripts (splice variants), 65 orthologues, 1 paralogue, is a member of 1 Ensembl protein family and is associated with 36 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
TMX1-001ENST000004573543995280aaENSP00000393316
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS41953Q9H3N1 NM_030755
NP_110382
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
TMX1-003ENST000005566832117105aaENSP00000451585
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-G3V448 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TMX1-002ENST00000555574943No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays