Description

caspase 1, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:1499]

Synonyms

ICE, IL1BC

Location

Chromosome 11: 105,025,443-105,035,250 reverse strand.

GRCh38:CM000673.2

About this gene

This gene has 16 transcripts (splice variants), 81 orthologues, 12 paralogues, is a member of 3 Ensembl protein families and is associated with 6 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CASP1-002ENST000005334002001404aaENSP00000433138
 
Protein coding
CCDS8330P29466 NM_001257118
NP_001244047
TSL:1GENCODE basicAPPRIS P4
CASP1-001ENST000004368631477404aaENSP00000410076
 
Protein coding
CCDS8330P29466 NM_033292
NP_150634
TSL:1GENCODE basicAPPRIS P4
CASP1-004ENST000005258251237383aaENSP00000434779
 
Protein coding
CCDS8329P29466 NM_001223
NM_001257119
NP_001214
NP_001244048
TSL:2GENCODE basicAPPRIS ALT2
CASP1-009ENST000005265681061311aaENSP00000434250
 
Protein coding
CCDS53704P29466 NM_033293
NP_150635
TSL:1GENCODE basic
CASP1-202ENST00000446369948263aaENSP00000403260
 
Protein coding
CCDS8331P29466 NM_033294
NP_150636
TSL:1GENCODE basic
CASP1-008ENST00000534497825263aaENSP00000436875
 
Protein coding
CCDS8331P29466 -TSL:5GENCODE basic
CASP1-201ENST0000035324742388aaENSP00000344132
 
Protein coding
CCDS8332P29466 NM_033295
NP_150637
TSL:1GENCODE basic
CASP1-010ENST0000053116630088aaENSP00000434303
 
Protein coding
CCDS8332P29466 -TSL:5GENCODE basic
CASP1-007ENST000005279791521367aaENSP00000432340
 
Protein coding
-G3V169 -TSL:5GENCODE basic
CASP1-005ENST000005289741402301aaENSP00000434259
 
Protein coding
-B4DVD8 -TSL:2GENCODE basic
CASP1-014ENST00000532439821236aaENSP00000435536
 
Protein coding
-H0YEC7 -CDS 5' incompleteTSL:5
CASP1-003ENST000005298711392110aaENSP00000431947
 
Nonsense mediated decay
-Q5FBZ0 -TSL:1
CASP1-006ENST000005265111202No protein-
 
Retained intron
---TSL:2
CASP1-012ENST00000528424578No protein-
 
Retained intron
---TSL:4
CASP1-011ENST00000532520525No protein-
 
Retained intron
---TSL:2
CASP1-013ENST00000527625424No protein-
 
Retained intron
---TSL:3

Gene-based displays