Description

polymerase (RNA) I polypeptide E, 53kDa [Source:HGNC Symbol;Acc:HGNC:17631]

Synonyms

FLJ13390, FLJ13970, PAF53, PRAF1

Location
INSDC coordinates

chromosome:GRCh38:CM000671.2:37485935:37503697:1

About this gene

This gene has 3 transcripts (splice variants), 62 orthologues, is a member of 1 Ensembl protein family and is associated with 45 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
POLR1E-001ENST000003777981868419aaENSP00000367029
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6611Q9GZS1 NM_001282766
NM_022490
NP_001269695
NP_071935
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
POLR1E-002ENST000003777922229481aaENSP00000367023
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q9GZS1 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POLR1E-004ENST000004420091805141aaENSP00000399887
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E7EX70 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays