Description

structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011]

Synonyms

CAP-E, hCAP-E, SMC2L1

INSDC coordinates

chromosome:GRCh38:CM000671.2:104094260:104141417:1

About this gene

This gene has 5 transcripts (splice variants), 71 orthologues, is a member of 1 Ensembl protein family and is associated with 154 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
SMC2-201ENST0000028639859921197aaENSP00000286398
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS35086A0A024R158 O95347 NM_001042551
NM_001265602
NM_006444
NP_001036016
NP_001252531
NP_006435
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

SMC2-001ENST0000037479359091197aaENSP00000363925
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS35086A0A024R158 O95347 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

SMC2-002ENST0000037478742661197aaENSP00000363919
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS35086A0A024R158 O95347 NM_001042550
NP_001036015
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

SMC2-004ENST00000440179705145aaENSP00000414999
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q5T821 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

SMC2-003ENST000004939551408166aaENSP00000431534
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
---TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays