Description

3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005]

Synonyms

HL

Location

Chromosome 1: 23,801,885-23,838,620 reverse strand.

GRCh38:CM000663.2

About this gene

This gene has 9 transcripts (splice variants), 68 orthologues, 1 paralogue, is a member of 2 Ensembl protein families and is associated with 3 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
HMGCL-002ENST000003744901600325aaENSP00000363614
 
Protein coding
CCDS243P35914 NM_000191
NP_000182
TSL:1GENCODE basicAPPRIS P1
HMGCL-007ENST000004364391354254aaENSP00000389281
 
Protein coding
CCDS53279P35914 NM_001166059
NP_001159531
TSL:2GENCODE basic
HMGCL-010ENST000002359581101182aaENSP00000235958
 
Protein coding
-H0Y2L7 -CDS 5' incompleteTSL:5
HMGCL-001ENST00000374487215177aaENSP00000363611
 
Nonsense mediated decay
-D6REN8 -TSL:2
HMGCL-008ENST000005093891379No protein-
 
Processed transcript
---TSL:1
HMGCL-006ENST00000496907858No protein-
 
Processed transcript
---TSL:3
HMGCL-003ENST00000479458594No protein-
 
Processed transcript
---TSL:3
HMGCL-004ENST00000498698463No protein-
 
Processed transcript
---TSL:3
HMGCL-009ENST000005131482011No protein-
 
Retained intron
---TSL:2

Gene-based displays