Description

mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:HGNC:6860]

Synonyms

c-COT, COT, EST, ESTF, MEKK8, Tpl-2

Location

Chromosome 10: 30,433,937-30,461,833 forward strand.

GRCh38:CM000672.2

About this gene

This gene has 7 transcripts (splice variants), 61 orthologues, 8 paralogues, is a member of 1 Ensembl protein family and is associated with 63 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP3K8-002ENST000002630563096467aaENSP00000263056
 
Protein coding
CCDS7166P41279 NM_005204
NP_005195
TSL:1GENCODE basicAPPRIS P1
MAP3K8-201ENST000005425472782467aaENSP00000443610
 
Protein coding
CCDS7166P41279 NM_001244134
NP_001231063
TSL:1GENCODE basicAPPRIS P1
MAP3K8-003ENST000003753212518467aaENSP00000364470
 
Protein coding
CCDS7166P41279 -TSL:1GENCODE basicAPPRIS P1
MAP3K8-004ENST000004151391026255aaENSP00000409653
 
Protein coding
-Q5T857 -CDS 3' incompleteTSL:3
MAP3K8-006ENST00000375322932132aaENSP00000364471
 
Protein coding
-Q5T854 -TSL:2GENCODE basic
MAP3K8-005ENST00000413724776223aaENSP00000391275
 
Protein coding
-Q5T853 -CDS 3' incompleteTSL:3
MAP3K8-001ENST00000430603647No protein-
 
Retained intron
---TSL:3

Gene-based displays