Description

adrenergic, beta, receptor kinase 2 [Source:HGNC Symbol;Acc:HGNC:290]

Synonyms

BARK2, GRK3

Location
INSDC coordinates

chromosome:GRCh38:CM000684.2:25564849:25729294:1

About this gene

This gene has 3 transcripts (splice variants), 69 orthologues, 6 paralogues, is a member of 2 Ensembl protein families and is associated with 101 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ADRBK2-001ENST000003241989103688aaENSP00000317578
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13832A0A024R1D8 P35626 NM_005160
NP_005151
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ADRBK2-201ENST000006199062873387aaENSP00000478925
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q8N433 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ADRBK2-002ENST0000045555865745aaENSP00000393688
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-H7C099 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays