Description

polycystic kidney disease 2-like 2 [Source:HGNC Symbol;Acc:HGNC:9012]

Synonyms

TRPP5

INSDC coordinates

chromosome:GRCh38:CM000667.2:137887968:137942747:1

About this gene

This gene has 7 transcripts (splice variants), 51 orthologues, 8 paralogues, is a member of 2 Ensembl protein families and is associated with 94 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PKD2L2-006ENST000005086382333523aaENSP00000423382
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS58971Q9NZM6 NM_001258449
NP_001245378
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PKD2L2-008ENST000002904312202613aaENSP00000290431
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS43367Q9NZM6 NM_014386
NP_055201
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P2

PRINCIPAL2 - APPRIS candidate principal isoform (CCDS).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PKD2L2-002ENST000005028102185602aaENSP00000425513
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS58972Q9NZM6 NM_001258448
NP_001245377
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PKD2L2-001ENST000005088832282624aaENSP00000424725
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q9NZM6 NM_001300921
NP_001287850
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PKD2L2-005ENST000005030151927182aaENSP00000424885
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-D6RF71 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PKD2L2-007ENST0000051117683084aaENSP00000423926
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-D6RBX8 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PKD2L2-003ENST0000041409493057aaENSP00000388060
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-Q9NZM6 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays