Description

exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662]

Synonyms

hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p

Location
INSDC coordinates

chromosome:GRCh38:CM000681.2:41386374:41397479:1

About this gene

This gene has 5 transcripts (splice variants), 62 orthologues, is a member of 2 Ensembl protein families and is associated with 28 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
EXOSC5-001ENST000002212331118235aaENSP00000221233
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS12580Q9NQT4 NM_020158
NP_064543
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

EXOSC5-005ENST00000596905826197aaENSP00000471002
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-M0R050 -TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
EXOSC5-004ENST00000593771404134aaENSP00000471557
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-M0R102 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

EXOSC5-003ENST0000060212935462aaENSP00000472396
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-M0R289 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

EXOSC5-002ENST00000593523716No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays