Description

ROS proto-oncogene 1 , receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10261]

Synonyms

c-ros-1, MCF3, ROS

INSDC coordinates

chromosome:GRCh38:CM000668.2:117288300:117425855:1

About this gene

This gene has 3 transcripts (splice variants), 50 orthologues, 13 paralogues, is a member of 1 Ensembl protein family and is associated with 501 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ROS1-001ENST0000036850874352347aaENSP00000357494
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5116P08922 NM_002944
NP_002935
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI2APPRIS candidate principal isoform (CCDS)
Glossary entry for APPRIS
APPRIS website
ROS1-002ENST0000036850774172341aaENSP00000357493
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q5H8Y1 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
ROS1-003ENST0000040328468197aaENSP00000384647
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H0Y3T9 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays