Description

glutamate-cysteine ligase, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311]

Synonyms

GCS, GLCL, GLCLC

Location

Chromosome 6: 53,497,341-53,616,970 reverse strand.

GRCh38:CM000668.2

About this gene

This gene has 13 transcripts (splice variants), 72 orthologues, is a member of 4 Ensembl protein families and is associated with 2 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
GCLC-001ENST000002294163813637aaENSP00000229416
 
Protein coding
CCDS4952P48506 Q14TF0 NM_001498
NP_001489
TSL:1GENCODE basicAPPRIS P1
GCLC-201ENST000006169233694599aaENSP00000482756
 
Protein coding
CCDS75471E1CEI4 NM_001197115
NP_001184044
TSL:1GENCODE basic
GCLC-003ENST000005140042356252aaENSP00000421908
 
Protein coding
-A0A0C4DGB2 -TSL:1GENCODE basic
GCLC-013ENST0000050519759218aaENSP00000427403
 
Protein coding
-D6RIT4 -CDS 3' incompleteTSL:4
GCLC-006ENST00000514933542154aaENSP00000423615
 
Protein coding
-D6R959 -CDS 3' incompleteTSL:5
GCLC-009ENST00000513939519173aaENSP00000424211
 
Protein coding
-H0Y9I7 -CDS 5' and 3' incompleteTSL:2
GCLC-010ENST0000051437332993aaENSP00000426578
 
Protein coding
-H0YAB6 -CDS 5' incompleteTSL:2
GCLC-008ENST00000504525101154aaENSP00000421228
 
Nonsense mediated decay
-D6RGF8 -TSL:3
GCLC-007ENST00000505294847122aaENSP00000421629
 
Nonsense mediated decay
-D6REX4 -TSL:3
GCLC-005ENST000005095413774No protein-
 
Retained intron
---TSL:5
GCLC-004ENST000005155802132No protein-
 
Retained intron
---TSL:1
GCLC-011ENST00000510837776No protein-
 
Retained intron
---TSL:2
GCLC-012ENST00000504353597No protein-
 
Retained intron
---TSL:3

Gene-based displays