Description

tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892]

Synonyms

DIF, TNF-alpha, TNFA, TNFSF2

Location

Chromosome 6: 31,575,567-31,578,336 forward strand.

View alleles of this gene on alternate assemblies

INSDC coordinates

chromosome:GRCh38:CM000668.2:31575567:31578336:1

About this gene

This gene has 1 transcript (splice variant), 7 gene alleles, 61 orthologues, 4 paralogues, is a member of 1 Ensembl protein family and is associated with 3 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
TNF-001ENST000004492641676233aaENSP00000398698
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS4702P01375 Q5STB3 NM_000594
NP_000585
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

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Gene-based displays