Description

retinoblastoma-like 1 [Source:HGNC Symbol;Acc:HGNC:9893]

Synonyms

cp107, p107, PRB1

Location
INSDC coordinates

chromosome:GRCh38:CM000682.2:36996349:37095995:1

About this gene

This gene has 4 transcripts (splice variants), 67 orthologues, 2 paralogues, is a member of 1 Ensembl protein family and is associated with 156 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
RBL1-001ENST0000037366456841068aaENSP00000362768
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13289P28749 NM_002895
NP_002886
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI4APPRIS candidate principal isoform (longest CCDS)
Glossary entry for APPRIS
APPRIS website
RBL1-002ENST0000034435932251014aaENSP00000343646
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13290P28749 NM_183404
NP_899662
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
RBL1-004ENST00000525052763255aaENSP00000434711
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H0YE05 -CDS 5' and 3' incomplete5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

RBL1-003ENST00000527999599113aaENSP00000437240
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E9PNB6 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays