Description

pleckstrin homology domain containing, family G (with RhoGef domain) member 4 [Source:HGNC Symbol;Acc:HGNC:24501]

Synonyms

ARHGEF44, DKFZP434I216, SCA4

Location
INSDC coordinates

chromosome:GRCh38:CM000678.2:67277510:67289499:1

Transcripts



This gene has 15 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
PLEKHG4-002ENST0000036046167821191 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS32466A0A024R6X4 C5IFI8 H3BME5
H3BPQ5 H3BQE6 H3BQP9
H3BSU4 Q58EX7
NM_001129727
NM_015432
NP_001123199
NP_056247
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
PLEKHG4-005ENST0000037934445131191 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS32466A0A024R6X4 C5IFI8 H3BME5
H3BPQ5 H3BQE6 H3BQP9
H3BSU4 Q58EX7
NM_001129729
NP_001123201
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
PLEKHG4-006ENST0000045073344801110 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS45512C5IFI8 H3BME5 H3BPQ5
H3BQE6 H3BQP9 H3BSU4
Q58EX7
NM_001129731
NP_001123203
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PLEKHG4-004ENST0000042715544551191 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS32466A0A024R6X4 C5IFI8 H3BME5
H3BPQ5 H3BQE6 H3BQP9
H3BSU4 Q58EX7
NM_001129728
NP_001123200
TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
PLEKHG4-011ENST0000056214457476 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BME5 H3BPQ5 H3BSU4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-012ENST0000056589956074 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BPQ5 H3BSU4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-013ENST00000565773542108 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C5IFI8 H3BME5 H3BPQ5
H3BQE6 H3BQP9 H3BSU4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-019ENST0000056862151436 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BSU4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-017ENST0000056274449164 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BQ60 H3BSU4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-016ENST00000569875489125 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3QSC9 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-018ENST0000056793846677 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BME5 H3BPQ5 H3BQE6
H3BSU4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-001ENST000005639696949193 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-C5IFI8 H3BME5 H3BPQ5
H3BQE6 H3BQP9 H3BSU4
Q58EX7
-TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-007ENST000003939662182193 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-C5IFI8 H3BME5 H3BPQ5
H3BQE6 H3BQP9 H3BSU4
Q58EX7
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-020ENST00000567136698106 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
---CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PLEKHG4-014ENST000005622891298No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays