Description

coagulation factor VIII, procoagulant component [Source:HGNC Symbol;Acc:HGNC:3546]

Synonyms

DXS1253E, F8C, FVIII, HEMA

INSDC coordinates

chromosome:GRCh38:CM000685.2:154835788:155026940:1

About this gene

This gene has 5 transcripts (splice variants), 49 orthologues, 8 paralogues, is a member of 1 Ensembl protein family and is associated with 6 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
F8-001ENST0000036025690592351aaENSP00000353393
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS35457P00451 NM_000132
NP_000123
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

F8-003ENST000003302872620216aaENSP00000327895
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS44026P00451 NM_019863
NP_063916
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
F8-004ENST00000423959791222aaENSP00000409446
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B1B0G8 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

F8-005ENST00000453950545165aaENSP00000389153
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B1B0G9 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

F8-002ENST00000483822461No protein-
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays