Description

NK2 homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2488]

Synonyms

CSX, CSX1, NKX2.5, NKX2E, NKX4-1

INSDC coordinates

chromosome:GRCh38:CM000667.2:173232109:173235357:1

About this gene

This gene has 4 transcripts (splice variants), 37 orthologues, 17 paralogues, is a member of 1 Ensembl protein family and is associated with 20 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
NKX2-5-001ENST000003291981709324aaENSP00000327758
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS4387P52952 NM_004387
NP_004378
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

NKX2-5-003ENST000004244061124112aaENSP00000395378
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS54950P52952 NM_001166175
NP_001159647
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NKX2-5-004ENST000005218481027151aaENSP00000427906
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS54949P52952 NM_001166176
NP_001159648
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NKX2-5-002ENST00000517440655142aaENSP00000429905
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RH49 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

Transcript Support Level 4, for transcripts supported by an EST flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays