Description

crumbs family member 2 [Source:HGNC Symbol;Acc:HGNC:18688]

Synonyms

FLJ16786, FLJ38464

INSDC coordinates

chromosome:GRCh38:CM000671.2:123356170:123380324:1

About this gene

This gene has 3 transcripts (splice variants), 64 orthologues, 14 paralogues, is a member of 1 Ensembl protein family and is associated with 160 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CRB2-001ENST0000037363155501285aaENSP00000362734
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6852Q5IJ48 NM_173689
NP_775960
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

CRB2-003ENST0000035999936591176aaENSP00000353092
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q5IJ48 -TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
CRB2-002ENST000004602533947953aaENSP00000435279
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-Q5IJ48 -TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays