Description

integral membrane protein 2C [Source:HGNC Symbol;Acc:HGNC:6175]

Synonyms

BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3

INSDC coordinates

chromosome:GRCh38:CM000664.2:230864639:230879248:1

About this gene

This gene has 10 transcripts (splice variants), 66 orthologues, 2 paralogues, is a member of 2 Ensembl protein families and is associated with 39 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ITM2C-001ENST000003264272078267aaENSP00000322730
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2479A0A024R466 Q9NQX7 NM_001287241
NM_030926
NP_001274170
NP_112188
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ITM2C-002ENST000003350051889220aaENSP00000335121
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS33396Q9NQX7 NM_001012514
NP_001012532
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITM2C-006ENST000003264071888230aaENSP00000322100
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS33395Q9NQX7 NM_001012516
NP_001012534
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITM2C-008ENST000004097041106205aaENSP00000387242
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS74665B8ZZM6 NM_001287240
NP_001274169
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITM2C-004ENST00000457215763180aaENSP00000390655
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JG41 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

Transcript Support Level 4, for transcripts supported by an EST flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITM2C-007ENST00000543957573122aaENSP00000444899
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F5H4I5 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITM2C-010ENST00000541852572125aaENSP00000440295
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7EUS6 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITM2C-009ENST00000418408563125aaENSP00000403257
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7EUS6 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

Transcript Support Level 4, for transcripts supported by an EST flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ITM2C-201ENST00000620962501166aaENSP00000480137
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q96JS4 -TSL:NA

Transcript Support Level Not Analysed. Pseudogenes, single exon transcripts, HLA, T-cell receptor and Ig transcripts are not analysed and therefore not given any of the TSL categories.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ITM2C-005ENST00000492029549No protein-
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays