Description

transmembrane protease, serine 11E [Source:HGNC Symbol;Acc:HGNC:24465]

Synonyms

DESC1, TMPRSS11E2

Location

Chromosome 4: 68,447,449-68,497,604 forward strand.

View alleles of this gene on alternate assemblies

INSDC coordinates

chromosome:GRCh38:CM000666.2:68447449:68497604:1

About this gene

This gene has 2 transcripts (splice variants), 1 gene allele, 42 orthologues, 13 paralogues, is a member of 1 Ensembl protein family and is associated with 74 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
TMPRSS11E-001ENST000003053632136423aaENSP00000307519
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS33993Q9UL52 NM_014058
NP_054777
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

TMPRSS11E-002ENST00000510647794125aaENSP00000424109
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-H0Y9G7 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays