Description

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6844]

Synonyms

JNKK1, MEK4, MKK4, PRKMK4, SERK1

Location

Chromosome 17: 12,020,824-12,143,830 forward strand.

GRCh38:CM000679.2

About this gene

This gene has 15 transcripts (splice variants), 75 orthologues, 6 paralogues, is a member of 5 Ensembl protein families and is associated with 177 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K4-002ENST000004153853856410aaENSP00000410402
 
Protein coding
CCDS62095P45985 NM_001281435
NP_001268364
TSL:2GENCODE basicAPPRIS ALT2
MAP2K4-001ENST000003535333826399aaENSP00000262445
 
Protein coding
CCDS11162P45985 NM_003010
NP_003001
TSL:1GENCODE basicAPPRIS P3
MAP2K4-011ENST00000602811113641aaENSP00000473582
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-012ENST00000602375106492aaENSP00000473472
 
Nonsense mediated decay
-R4GN37 -TSL:5
MAP2K4-014ENST0000060268697741aaENSP00000473458
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-013ENST0000060230596145aaENSP00000473606
 
Nonsense mediated decay
-J3QLE2 -TSL:5
MAP2K4-015ENST0000060253794841aaENSP00000473511
 
Nonsense mediated decay
-R4GN68 -TSL:5
MAP2K4-008ENST0000053846592516aaENSP00000467239
 
Nonsense mediated decay
-K7EP58 -CDS 5' incompleteTSL:5
MAP2K4-010ENST0000058218355145aaENSP00000463507
 
Nonsense mediated decay
-J3QLE2 -TSL:4
MAP2K4-003ENST00000581941813No protein-
 
Processed transcript
---TSL:3
MAP2K4-009ENST00000579089571No protein-
 
Processed transcript
---TSL:4
MAP2K4-006ENST00000582897482No protein-
 
Processed transcript
---TSL:5
MAP2K4-005ENST000005364133852No protein-
 
Retained intron
---TSL:2
MAP2K4-004ENST00000582377648No protein-
 
Retained intron
---TSL:3
MAP2K4-007ENST00000585076543No protein-
 
Retained intron
---TSL:4

Gene-based displays