Description

mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]

Synonyms

MAPKK3, MEK3, MKK3, PRKMK3

Location

Chromosome 17: 21,284,672-21,315,240 forward strand.

GRCh38:CM000679.2

About this gene

This gene has 15 transcripts (splice variants), 52 orthologues, 6 paralogues, is a member of 5 Ensembl protein families and is associated with 100 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K3-001ENST000003426792303347aaENSP00000345083
 
Protein coding
CCDS11217P46734 Q6FI23 NM_145109
NP_659731
TSL:1GENCODE basicAPPRIS P1
MAP2K3-201ENST000003618182034318aaENSP00000355081
 
Protein coding
CCDS11218P46734 NM_002756
NP_002747
TSL:5GENCODE basic
MAP2K3-202ENST000006133382029318aaENSP00000478619
 
Protein coding
CCDS11218P46734 -TSL:1GENCODE basic
MAP2K3-013ENST000003169201246318aaENSP00000319139
 
Protein coding
CCDS11218P46734 -TSL:5GENCODE basic
MAP2K3-016ENST00000526076575160aaENSP00000434068
 
Protein coding
-E9PRZ0 -CDS 3' incompleteTSL:4
MAP2K3-014ENST00000527123535136aaENSP00000462178
 
Protein coding
-J3KRV4 -CDS 5' incompleteTSL:4
MAP2K3-011ENST00000529517514101aaENSP00000431203
 
Protein coding
-E9PMA8 -CDS 3' incompleteTSL:4
MAP2K3-203ENST0000062744735146aaENSP00000486923
 
Protein coding
---TSL:5GENCODE basic
MAP2K3-002ENST00000395491240146aaENSP00000378869
 
Nonsense mediated decay
-X6RB39 -TSL:2
MAP2K3-004ENST000004960462089173aaENSP00000464043
 
Nonsense mediated decay
-J3QR49 -TSL:5
MAP2K3-006ENST0000047912957446aaENSP00000463417
 
Nonsense mediated decay
-J3QL77 -TSL:3
MAP2K3-007ENST0000048392851146aaENSP00000463202
 
Nonsense mediated decay
-J3QL77 -TSL:5
MAP2K3-010ENST00000534743541No protein-
 
Processed transcript
---TSL:4
MAP2K3-009ENST00000477540927No protein-
 
Retained intron
---TSL:2
MAP2K3-017ENST00000583508607No protein-
 
Retained intron
---TSL:5

Gene-based displays