Description

POU class 5 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9221]

Synonyms

MGC22487, OCT3, Oct4, OTF3

Location

Chromosome 6: 31,164,337-31,180,731 reverse strand.

View alleles of this gene on alternate assemblies

INSDC coordinates

chromosome:GRCh38:CM000668.2:31164337:31180731:1

About this gene

This gene has 9 transcripts (splice variants), 6 gene alleles, 66 orthologues, 15 paralogues, is a member of 1 Ensembl protein family and is associated with 92 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
POU5F1-005ENST000005134072276164aaENSP00000475512
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS75420F2Z381 NM_001285986
NP_001272915
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-002ENST000004715291723164aaENSP00000425083
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS75420F2Z381 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-202ENST000006200311578190aaENSP00000484778
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS47398U3KQH6 NM_001173531
NM_001285987
NM_203289
NP_001167002
NP_001272916
NP_976034
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-001ENST000002599151420360aaENSP00000259915
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS34391D2IYK3 Q01860 NM_002701
NP_002692
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
POU5F1-007ENST000006065671236190aaENSP00000475880
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS47398U3KQH6 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-006ENST000005128181233164aaENSP00000425479
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS75420F2Z381 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-004ENST000004418881055164aaENSP00000389359
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS75420F2Z381 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-201ENST000006193401084186aaENSP00000481679
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WYB7 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
POU5F1-003ENST00000461401791No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene-based displays