Description

major histocompatibility complex, class II, DR beta 1 [Source:HGNC Symbol;Acc:HGNC:4948]

Synonyms

HLA-DR1B

Location

Chromosome 6: 32,552,990-32,589,848 reverse strand.

View alleles of this gene on alternate assemblies

INSDC coordinates

chromosome:GRCh38:CM000668.2:32552990:32589848:1

About this gene

This gene has 2 transcripts (splice variants), 5 gene alleles, 217 orthologues, 13 paralogues, is a member of 1 Ensembl protein family and is associated with 8 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
HLA-DRB1-001ENST000003600041229266aaENSP00000353099
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS47409D7RIH8 P01911 P04229
Q29974 Q9GIY3 X5DNQ0
NM_002124
NP_002115
TSL:NA

Transcript Support Level Not Analysed. Pseudogenes, single exon transcripts, HLA, T-cell receptor and Ig transcripts are not analysed and therefore not given any of the TSL categories.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P2

PRINCIPAL2 - APPRIS candidate principal isoform (CCDS).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

HLA-DRB1-201ENST00000611060920266aaENSP00000480667
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WX18 -TSL:NA

Transcript Support Level Not Analysed. Pseudogenes, single exon transcripts, HLA, T-cell receptor and Ig transcripts are not analysed and therefore not given any of the TSL categories.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT1

ALTERNATIVE1 - APPRIS candidate principal isoform that is conserved in at least three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Genomic alignments
Gene tree
Orthologues
Paralogues
Families

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene-based displays