Description

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) [Source:HGNC Symbol;Acc:HGNC:9604]

Synonyms

COX1, PGHS-1, PTGHS

Location

Chromosome 9: 122,370,530-122,395,703 forward strand.

GRCh38:CM000671.2

About this gene

This gene has 7 transcripts (splice variants), 75 orthologues, 1 paralogue, is a member of 2 Ensembl protein families and is associated with 15 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PTGS1-202ENST000005407535375537aaENSP00000437709
 
Protein coding
CCDS59520P23219 NM_001271368
NP_001258297
TSL:2GENCODE basic
PTGS1-201ENST000003736984987490aaENSP00000362802
 
Protein coding
CCDS59521P23219 NM_001271165
NM_001271166
NM_001271367
NP_001258094
NP_001258095
NP_001258296
TSL:2GENCODE basic
PTGS1-001ENST000003620124964599aaENSP00000354612
 
Protein coding
CCDS6842P23219 NM_000962
NP_000953
TSL:1GENCODE basicAPPRIS P2
PTGS1-203ENST000006149104894551aaENSP00000484800
 
Protein coding
CCDS75895A0A087X296 NM_001271164
NP_001258093
TSL:3GENCODE basic
PTGS1-002ENST000002234232328562aaENSP00000223423
 
Protein coding
CCDS6843P23219 NM_080591
NP_542158
TSL:1GENCODE basic
PTGS1-204ENST000006193065051630aaENSP00000483540
 
Protein coding
-P23219 -TSL:5GENCODE basicAPPRIS ALT2
PTGS1-003ENST00000426608468156aaENSP00000411606
 
Protein coding
-X6RJD6 -CDS 5' and 3' incompleteTSL:5
Genomic alignments
Gene tree
Orthologues
Paralogues
Families

More views of comparative genomics data, such as multiple alignments and synteny, are available on the Location page for this gene.

Gene-based displays