Gene: aph1b ENSDARG00000005612

Description

APH1B gamma secretase subunit [Source:NCBI gene (formerly Entrezgene);Acc:386808]

Gene Synonyms

APH1A, psfl, wu:fc41h05, wu:fi53a04

Location

GRCz11:CM002891.2

About this gene

This gene has 3 transcripts (splice variants), 184 orthologues, 1 paralogue and is associated with 7 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000008096.8	aph1b-201	1974	258aa	ENSDARP00000011743.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q8JHE9	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSDART00000146655.3	aph1b-203	728	No protein	-	Gene/transcript that doesn't contain an open reading frame (ORF).Processed transcript	-	-
ENSDART00000145129.2	aph1b-202	500	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron	-	-

Summary